{"product_id":"cfebaunpspe","title":"Gold (Au) Nanoparticle Modified Screen-Printed Electrode as Flexible Electrochemical Biosensors, CFEBAuNPSPE","description":"\u003cp\u003eA Gold Nanoparticle Modified Screen-Printed Electrode (AuNP-SPE) integrates the catalytic activity, high electroactive surface area (EASA), and self-assembly chemistry of nanostructured gold with the cost efficiency, reproducibility, and disposable format of thick-film screen printing.\u003c\/p\u003e\n\u003cp\u003eAuNP-SPEs are configured as a miniaturized planar three-electrode cell on a polymer (PET, PI) or alumina ceramic substrate, requiring only 20 to 50 uL of sample droplet:  \u003cem\u003eWorking Electrode (WE)\u003c\/em\u003e: Typically a carbon or gold conductive core (Φ 2–4 mm) functionalized with AuNPs. \u003cem\u003eCounter Electrode (CE)\u003c\/em\u003e: High-surface-area curved carbon or platinum band. \u003cem\u003eReference Electrode (RE)\u003c\/em\u003e: Printed Ag\/AgCl pseudoreference ink. \u003cem\u003eDielectric Mask:\u003c\/em\u003e Hydrophobic polymer layer confining the sample droplet to the sensing zone.\u003c\/p\u003e\n\u003cp\u003eThe electrochemical \u0026amp; interfacial advantages are: (1) \u003cstrong\u003eThiol Chemisorption for Bioreceptors (Au-S Bonds)\u003c\/strong\u003e: Forms strong, spontaneous, covalent gold–thiol bonds (~ 184 kJ\/mol). This allows direct immobilization of thiolated DNA\/RNA hairpins, aptamers, and cysteine-modified antibodies into dense self-assembled monolayers (SAMs) without harsh cross-linkers. (2) \u003cstrong\u003eAccelerated Heterogeneous Electron Transfer\u003c\/strong\u003e: AuNPs serve as conductive electron relays between redox centers (e.g., ferrocene, methylene blue, or enzyme prosthetic groups like FAD) and the underlying carbon substrate, reducing charge-transfer resistance in electrochemical impedance spectroscopy (EIS). (3) \u003cstrong\u003eElectroactive Surface Area (EASA) Determination\u003c\/strong\u003e: The true electrochemically active area is characterized by cyclic voltammetry in 0.5 M H2SO4 scanning from 0.0 to +1.5 V vs. Ag\/AgCl.\u003c\/p\u003e\n\u003cp\u003eThe primary analytical applications are: (1) \u003cstrong\u003eElectrochemical Biosensors \u0026amp; Immunoassays\u003c\/strong\u003e: Detection of cardiac biomarkers (cTnI), cancer antigens (PSA, CA-125), and viral pathogens via sandwich or competitive assays. E-DNA sensors where target hybridization alters the distance of a redox tag from the gold surface, modulating Faradaic current. (2) \u003cstrong\u003eAnodic Stripping Voltammetry (ASV) for Heavy Metals\u003c\/strong\u003e: Exceptional selectivity for trace Arsenic (As^{3+}) and Mercury (Hg^{2+}). Under negative pre-concentration potentials, gold forms stable intermetallic\/amalgam species with the reduced metals, achieving sub-ppb limits of detection. (3) \u003cstrong\u003eNon-Enzymatic Catalytic Sensing\u003c\/strong\u003e: Direct electrocatalytic oxidation of glucose, hydrogen peroxide (H2O2), and hydrazine at lower overpotentials than bare carbon or platinum electrodes.\u003c\/p\u003e\n\u003ctable border=\"1\" style=\"width: 100.071%; height: 431.2px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 47.6px;\"\u003e\n\u003ctd style=\"width: 24.8016%; height: 47.6px;\"\u003ePart Number\u003c\/td\u003e\n\u003ctd style=\"width: 74.9846%; height: 47.6px;\"\u003e\n\u003cul\u003e\n\u003cli\u003eCFEBAuNPSPE (C-FEB-AuNPSPE)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 383.6px;\"\u003e\n\u003ctd style=\"width: 24.8016%; height: 383.6px;\"\u003eCritical Features\u003c\/td\u003e\n\u003ctd style=\"width: 74.9846%; height: 383.6px;\"\u003e\n\u003cul\u003e\n\u003cli\u003eSubstrate Material: PET (thickness=0.28 mm)\u003c\/li\u003e\n\u003cli\u003eWorking Electrode (WE): Gold Nanoparticle Film (Φ 5mm)\u003c\/li\u003e\n\u003cli\u003eCounter Electrode (CE): Carbon\u003c\/li\u003e\n\u003cli\u003eReference Electrode (RE): Ag\/AgCl\u003c\/li\u003e\n\u003cli\u003eElectrode Size:\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e       \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0774\/6591\/1526\/files\/CEBAuNPSPE_02_160x160.jpg?v=1788599509\" alt=\"\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTesting Performance:\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e          \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0774\/6591\/1526\/files\/CEBAuNPSPE_03_160x160.jpg?v=1788600035\" style=\"margin-bottom: 16px; float: none;\"\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAn adapter is included for operation. \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e           \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0774\/6591\/1526\/files\/CEBAuNPSPE_05_100x100.jpg?v=1788600422\" alt=\"\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eStorage Conditions: RT, avoid light illumination, Al bags sealing, ~50%RH \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 24.8016%;\"\u003ePackage Grade\u003c\/td\u003e\n\u003ctd style=\"width: 74.9846%;\"\u003e\n\u003cul\u003e\n\u003cli\u003e10 pcs\/pack\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e:\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/pubs.acs.org\/nalefd\/article-abstract\/3\/9\/1203\/3799331\/Nanostructured-Electrochemical-Sensor-Based-on?redirectedFrom=fulltext\"\u003eA. Yu, et al., Nanostructured Electrochemical Sensor Based on Dense Gold Nanoparticle Films, Nanostructured Electrochemical Sensor Based on Dense Gold Nanoparticle Films\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/link.springer.com\/article\/10.1007\/s00216-005-3221-5\"\u003eP. Yáñez-Sedeño. et al. Gold nanoparticle-based electrochemical biosensors, Analytical and Bioanalytical Chemistry, 2005, 382,  884–886.\u003c\/a\u003e \u003c\/li\u003e\n\u003c\/ol\u003e","brand":"HYKJ","offers":[{"title":"Default Title","offer_id":48288279265510,"sku":"CFEBAuNPSPE","price":199.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0774\/6591\/1526\/files\/CFEBAuNPSPE_main.jpg?v=1788631983","url":"https:\/\/echemsupplies.com\/products\/cfebaunpspe","provider":"EChem Supplies","version":"1.0","type":"link"}