{"product_id":"crhshamapba","title":"HAMA-PBA (Phenylboronic Acid-Modified Methacrylated Hyaluronic Acid) Powder for Responsive Hydrogel Synthesis, 0.5 g\/bottle, CRHSHAMAPBA","description":"\u003cp\u003eHAMA-PBA (Phenylboronic Acid-Modified Methacrylated Hyaluronic Acid) is an advanced, dual-crosslinkable biopolymer designed for sophisticated tissue engineering, 3D bioprinting, and responsive drug delivery systems. By combining both methacrylate groups (for rapid, permanent photo-crosslinking) and phenylboronic acid groups (for dynamic, stimuli-responsive, and self-healing covalent interactions), HAMA-PBA allows you to create hydrogels with tunable mechanical stiffness, shear-thinning injectability, and environmental responsiveness (to glucose, pH, or reactive oxygen species).\u003c\/p\u003e\n\u003ctable style=\"width: 100.029%; height: 524.688px;\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 35.6px;\"\u003e\n\u003ctd style=\"width: 33.0409%; height: 35.6px;\"\u003e\u003cem\u003ePart Number\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.8129%; height: 35.6px;\"\u003e\n\u003cp\u003e\u003cspan\u003eCRHSHAMAPBA (C-RHS-HAMAPBA)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 88.4px;\"\u003e\n\u003ctd style=\"width: 33.0409%; height: 88.4px;\"\u003e\u003cem\u003eChemical Formula\/Structure\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.8129%; height: 88.4px;\"\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0774\/6591\/1526\/files\/CRHSHAMAPBA_Structure.jpg?v=1792089879\" alt=\"\"\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.2px;\"\u003e\n\u003ctd style=\"width: 33.0409%; height: 39.2px;\"\u003e\u003cem\u003eMolecular Weight\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.8129%; height: 39.2px;\"\u003e\n\u003cdiv style=\"text-align: start;\"\u003eMw=100000 (other molecular weight of 50000 also can be supplied upon request)\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 140.4px;\"\u003e\n\u003ctd style=\"width: 33.0409%; height: 140.4px;\"\u003e\u003cem\u003eNMR\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.8129%; height: 140.4px;\"\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0774\/6591\/1526\/files\/CRHSHAMAPBA_NMR_160x160.jpg?v=1792090014\" style=\"margin-bottom: 16px; float: none;\"\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 185.2px;\"\u003e\n\u003ctd style=\"width: 33.0409%; height: 185.2px;\"\u003e\u003cem\u003eHydrogel Preparation Steps\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.8129%; height: 185.2px;\"\u003e\n\u003cp\u003e(1). \u003cstrong\u003e0.25% (2.5 mg\/mL) photoinitiator solution preparation\u003c\/strong\u003e: Add 20 mL PBS into the 0.05 g LAP brown bottle and heat it for 15 min at 40-50°C for complete dissolution.  \u003c\/p\u003e\n\u003cp\u003e(2) \u003cstrong\u003e4% HAMA-PBA solution preparation\u003c\/strong\u003e: Weigh 0.4g HAMA-PBA  powder and dissolve it in 1 mL PBS+LAP solution . Heat it up to 50°C until the mixture becomes clear (1- 4 h).\u003c\/p\u003e\n\u003cp\u003e(3) \u003cstrong\u003e3% PVA solution preparation\u003c\/strong\u003e: Weigh 0.03 g PVA powder and dissolve it in 1 mL PBS+LAP solution, and heat it at 50°C for 1-4 h until it becomes clear.\u003c\/p\u003e\n\u003cp\u003e(4) \u003cstrong\u003eHydrogel Formation\u003c\/strong\u003e: Take 200 uL 4% HAMA-PBA solution and mix with 100 uL 3% PVA solution and then add 5 uL 1 M NaOH to form gel. \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 33.0409%;\"\u003e\u003cem\u003eStorage Conditions\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.8129%;\"\u003e\n\u003cp\u003eStore it at 2-8 °C (avoid light) for upto 7 days. \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.8875px;\"\u003e\n\u003ctd style=\"width: 33.0409%; height: 35.8875px;\"\u003e\u003cem\u003ePackage Size\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.8129%; height: 35.8875px;\"\u003e0.5 g\/bottle\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eNotes\u003c\/strong\u003e: Please try to store the HAMA-PBA powder in a dry \u0026amp; cold place. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e: \u003c\/span\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1742706122003233\"\u003e\u003cspan\u003eZ. Xu, et al. Hyaluronic acid-based glucose-responsive antioxidant hydrogel platform for enhanced diabetic wound repair, Acta Biomaterialia, 2022, 147, 147-157\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003ca href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S2772950825003401\"\u003eZ. Lin, et al. Smart responsive injectable hydrogel loaded with icariin inhibits ferroptosis and promotes nucleus pulposus repair in intervertebral disc degeneration, Biomaterials Advances, 2026, 179, 214513\u003c\/a\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"YXSW","offers":[{"title":"Default Title","offer_id":67777697284326,"sku":"CRHSHAMAPBA","price":279.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0774\/6591\/1526\/files\/CRHSHAMAPBA_main.jpg?v=1792136639","url":"https:\/\/echemsupplies.com\/products\/crhshamapba","provider":"EChem Supplies","version":"1.0","type":"link"}