{"product_id":"crhshapba","title":"HA-PBA (Phenylboronic Acid-functionalized Hyaluronic Acid) Powder for Responsive Hydrogel Synthesis, 1 g\/bottle, CRHSHAPBA","description":"\u003cp\u003eHA-PBA (Phenylboronic Acid-functionalized Hyaluronic Acid) is a key polymer building block for creating smart, stimuli-responsive hydrogels. Because phenylboronic acid reversibly forms dynamic covalent ester bonds with cis-diol-containing molecules (such as sugars, polyvinyl alcohol, or catechol derivatives), HA-PBA hydrogels exhibit exceptional self-healing, injectability, and responsiveness to environments like glucose or reactive oxygen species (ROS).\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100.029%; height: 477.887px;\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 35.6px;\"\u003e\n\u003ctd style=\"width: 33.0409%; height: 35.6px;\"\u003e\u003cem\u003ePart Number\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.8129%; height: 35.6px;\"\u003e\n\u003cp\u003e\u003cspan\u003eCRHSHAPBA (C-RHS-HAPBA)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 106.4px;\"\u003e\n\u003ctd style=\"width: 33.0409%; height: 106.4px;\"\u003e\u003cem\u003eChemical Formula\/Structure\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.8129%; height: 106.4px;\"\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0774\/6591\/1526\/files\/CRHSHAPBAP_Structure_160x160.jpg?v=1792003207\" style=\"margin-bottom: 16px; float: none;\"\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.2px;\"\u003e\n\u003ctd style=\"width: 33.0409%; height: 39.2px;\"\u003e\u003cem\u003eMolecular Weight\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.8129%; height: 39.2px;\"\u003e\n\u003cdiv style=\"text-align: start;\"\u003eMw=100000 (other molecular weight of 50000 and 400000 also can be supplied upon request)\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 140.4px;\"\u003e\n\u003ctd style=\"width: 33.0409%; height: 140.4px;\"\u003e\u003cem\u003eNMR\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.8129%; height: 140.4px;\"\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0774\/6591\/1526\/files\/CRHSHAPBAP_NMR_160x160.jpg?v=1792003451\" style=\"margin-bottom: 16px; float: none;\"\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 120.4px;\"\u003e\n\u003ctd style=\"width: 33.0409%; height: 120.4px;\"\u003e\u003cem\u003eHydrogel Preparation Steps\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.8129%; height: 120.4px;\"\u003e\n\u003cp\u003e(1). \u003cstrong\u003e2% HA-PBA solution preparation\u003c\/strong\u003e: Weigh 0.02 g HA-PBA powder and dissolve it in 1 mL PBS under ultrasonic assistance for 1-4 h. \u003c\/p\u003e\n\u003cp\u003e(2) \u003cstrong\u003e3% PVA solution preparation\u003c\/strong\u003e: Weigh 0.03 g PVA powder and dissolve it in 1 mL PBS. Heat it up to 50°C until the mixture becomes clear (1- 4 h).\u003c\/p\u003e\n\u003cp\u003e(3) Take 400 uL 2% HA-PBA solution and slowly add the 200 uL 3% PVA solution under stirring. The hydrogel will form under vibration. \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.8875px;\"\u003e\n\u003ctd style=\"width: 33.0409%; height: 35.8875px;\"\u003e\u003cem\u003ePackage Size\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 66.8129%; height: 35.8875px;\"\u003e1 g\/bottle\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eNotes\u003c\/strong\u003e: Please try to store the HA-PBA powder in a dry place. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e: \u003c\/span\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\u003cspan\u003e\u003ca href=\"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/full\/10.1002\/advs.202304861\"\u003eS. Y. Cheon, et al. Injectable and Self-Curing Single-Component Hydrogel for Stem Cell Encapsulation and In Vivo Bone Regeneration, Adv. Sci., 2024, 11, 2304861\u003c\/a\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0144861719314717\"\u003e\u003cspan\u003eW. Shi, et al. Fabrication of versatile dynamic hyaluronic acid-based hydrogels, Carbohydrate Polymers, 2020, 233, 115803\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"YXSW","offers":[{"title":"Default Title","offer_id":67742119461094,"sku":"CRHSHAPBA","price":349.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0774\/6591\/1526\/files\/CRHSHAPBA_main.jpg?v=1792136478","url":"https:\/\/echemsupplies.com\/products\/crhshapba","provider":"EChem Supplies","version":"1.0","type":"link"}