GelMA (Gelatin Methacrylate) Powder for Photocurable Hydrogel Synthesis, 1 g/bottle, CPCHSGelMA
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GelMA (Gelatin Methacrylate) is one of the most widely used photocrosslinkable biopolymers for tissue engineering, 3D bioprinting, and cell encapsulation. By grafting methacrylate groups onto the amine-rich backbone of hydrolyzed collagen (gelatin), GelMA allows for rapid, cytocompatible photo-crosslinking under UV or visible light in the presence of a photoinitiator.
| Part Number |
CPCHSGelMA (C-PCHS-GelMA) |
| Chemical Formula/Structure |
 |
| Degree of Substitution |
(1) ~30%, compression modulus: 1-10 kPa, suitable for cell culture and drug delivery.
(2) ~60%, compression modulus: 3.5-22 kPa, suitable for soft tissue engineering and microfluid chip
(3) ~90%, compression modulus: 5.12-48 kPa, suitable for 3D bioprinting and support bracket
 |
| Photoinitiator |
The photoinitiator LAP (0.05 g) is included.
|
| Hydrogel Preparation Steps |
(1). 0.25% (2.5 mg/mL) photoinitiator PLA solution preparation: Take 20 mL PBS into 0.05 g LAP brown bottle and heated it at 40-50°C for 15 min. Several times of manual vibration can be applied. (2) 5-30% (50-300 mg/mL) GelMA solution preparation: Weigh calculated amount of GelMA powder into a centrifuge tube and add the photoinitiator PLA solution for mixing. Heat it up to 60-70 °C until full dissolution (avoid light). (3) Gel Formation: Expose the mixing solution at 405 nm light source. The hydrogel strength can be adjusted by illumination time and light intensity. |
| Storage Conditions |
Store it at -20°C (18 months), and 4°C for use in 7 days after de-freeze. |
| Package Size | 1 g/bottle |
References:
- Y. C. Chen, et al. Functional Human Vascular Network Generated in Photocrosslinkable Gelatin Methacrylate Hydrogels, Adv. Funct. Mater., 2012, 22, 2027-2039
- J. Ramón-Azcón, et al. Gelatin methacrylate as a promising hydrogel for 3D microscale organization and proliferation of dielectrophoretically patterned cells, Lab Chip (2012) 12 (16): 2959–2969.