Gel-PBA (Phenylboronic Acid Modified Gelatin) Powder for Responsive Hydrogel Synthesis, 1 g/bottle, CRHSGelPBA

Gel-PBA (Phenylboronic Acid-Modified Gelatin) is a smart, bioactive biopolymer that combines the natural cell-adhesion properties and biocompatibility of gelatin with the dynamic, stimuli-responsive cross-linking capabilities of phenylboronic acid (PBA). Because gelatin contains abundant carboxylic acid and amine residues, it can be readily functionalized with PBA to create injectable, self-healing hydrogels that respond to environmental cues such as pH changes, glucose concentrations, or reactive oxygen species (ROS).

Part Number	CRHSGelPBA (C-RHS-GelPBA)
Function Groups in Gelatin	(1) -NH2 (2) -COOH
NMR
Hydrogel Preparation Steps	(1). 10-30% Gel-PBA precursor solution: Weigh certain amount of Gel-PBA powder into centrifuge tubes and add the PBS solution for fully immersion. Heat it to 50°C (avoid light) for 10-20 min until full dissolution.  (2) 6% PVA solution preparation: Take certain amount of PVA into centrifuge tube and add PBS solution for mixing. Then heating at 50-60°C for 1-4 h until clear solution obtained. (3) Hydrogel Formation: Take 200 uL 10% Gel-PBA precursor solution, 5 uL 1 M NaOH, and 100 uL 6% PVA solution together to form gel.
Storage Conditions	Store it at 2-8 °C (avoid light) for upto 7 days.
Package Size	0.5 g/bottle

Notes: Please try to store the Gel-PBA powder in a dry & cold place. 

References: 

1. L. Zhao, et al. Self-regulating hydrogel for diabetic wound healing: From animal models to a pilot clinical study, Sci. Adv., 2026, DOI: 10.1126/sciadv.aed4981
2. J. Li, et al. Wound microenvironment self-adaptive all-in-one hydrogel for rapid healing of the diabetic wound, J. Mater. Chem. B (2024) 12 (8): 2070–2082.